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ANTIGENS, CD80
Descriptors Found:
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DeCS
Descriptor
English
:
Antigens, CD80
Descriptor
Spanish
:
Antígenos CD80
Descriptor
Portuguese
:
Antígenos CD80
Synonyms
English
:
Antigen, B7-1
B7-1 Antigen
B7-1 Ligand
CD80 Antigen
Antigen, B7 1
B Cell Activation Antigen
B7 1 Antigen
B7 1 Costimulatory Molecule
B7 1 Ligand
Costimulatory Molecule, B7-1
Ligand, B7-1
B-Cell Activation Antigen
CD80 Antigens
B7-1 Costimulatory Molecule
Tree Number:
D12.776.467.150.100
D12.776.543.095.100
D23.050.301.264.035.276.100
D23.050.301.285.100
D23.101.100.110.276.100
D23.529.168.100
Definition
English
:
A costimulatory ligand expressed by
ANTIGEN-PRESENTING CELLS
that binds to
CTLA-4 ANTIGEN
with high specificity and to CD28
ANTIGEN
with low specificity. The interaction of CD80 with CD28
ANTIGEN
provides a costimulatory signal to
T-LYMPHOCYTES
, while its interaction with
CTLA-4 ANTIGEN
may play a role in inducing
PERIPHERAL TOLERANCE.
History Note
English
:
96; was B-CELL ACTIVATION ANTIGEN 1994-95; was B CELL ACTIVATION ANTIGEN B7 (NM) 1991-93; B7-1 COSTIMULATORY MOLECULE was B7-1 PROTEIN (NM) 1994-95
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
31626
Unique Identifier:
D018122
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS